Delta-9-Tetra-Hydro-Cannabinol or more commonly known as THC, is one of more than one hundred cannabinoids (active ingredients in cannabis) discovered to date and is considered one of the most famous among them. It got its name mainly because it is responsible for the familiar “hi” effect of cannabis, but also because it is present in the plant in higher percentages than any other cannabinoid.
THC was first isolated from the plant in 1964, by Israeli chemists Professor Rafael Meshulam and Dr. Yechiel Gaoni, who worked with a team of researchers from the Hebrew University and the Weizmann Institute.
THC is a product of a process called ‘decarboxylation’ and is formed from the cannabinoid acid THCA found in cannabis flowers, mainly in their trichomes. Only after heating the THCA to a temperature of over 155-165 degrees is the THC released and causes the familiar “hi” effect. This is also the reason why cannabis harvested from the plant and swallowed will not have a psychoactive effect. When THC is oxidized (exposed to air), aged or damaged, it is converted to CBN, That is, the more THC disappears, the higher the amount of CBN and its effect.
When we smoke cannabis the THC will binds to receptors in the brain and nervous system, called cannabinoid receptors, These receptors are part of the endocannabinoid system in the human body. THC binds to two types of receptors, CB1 and CB2, which are scattered in different parts of the body: the spine, the immune system and especially the brain. Its absorption releases dopamine in the brain and leads to a feeling of euphoria and just being in a good mood.
The long-term effects are not yet clear to the world of science due to a lack of comprehensive studies, but so far no harm or benefit has been recorded that is directly attributed to THC consumption, even in large quantities and over a long period of time.
THC is considered a powerful analgesic, effective in fighting cancer cells and helps treat diseases such as glaucoma, parkinson’s, appetizer, multiple sclerosis and more.
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